Searchable abstracts of presentations at key conferences in endocrinology

ea0099p560 | Reproductive and Developmental Endocrinology | ECE2024

Dampened HPG axis activity and improved reproductive lifespan in dummerstorf superfertile mouse lines

Weitzel Joachim , Carolin Ludwig , Marten Michaelis

Research in the field of reproductive biology is largely based on informative mouse models. Almost all of these mouse models (~99%) exhibit an unfavourable reproductive phenotype - these mouse models are subfertile or infertile in one or possibly both sexes. In contrast, the number of animal models that show an enhanced reproductive phenotype is extremely rare. Nevertheless, these mouse models could be very informative in identifying mechanisms and pathways associated with enh...